Breaker19 is an Uber-like truck booking platform founded by two Houstonians. Photo via Getty Images

In a world where ”the customer is always right," two Houston founders have followed that rule right to their next venture.

Breaker19 — a groundbreaking mobile application built in late 2023 to be an efficient oilfield trucking and hotshot marketplace — was co-founded by Rodney Giles and Tyler Cherry. The native Houstonians also co-founded BidOut, a leading Oil & Gas procurement platform in 2021.

“About a year ago, one of our BidOut clients, a large operator, came to us and basically said that the biggest problem they have in the oil field is ordering trucks,” remembers Giles. “From there, they asked would we be willing to build something similar to Uber, but for oilfield logistics and trucking? So, we built Breaker19.”

After their customer presented a challenge, Giles and Cherry got to work. They envisioned the technical architecture almost immediately and assembled a team of software engineers to build an in-house application in less than a year.

“We launched Breaker19 in November 2023, and my goodness, it has taken off like crazy,” says Giles. “It is growing incredibly fast. We’re doing hundreds of truckloads a day now, all throughout West Texas, South Texas, North Dakota, really all over the U.S.”

Now, armed with such large publicly traded companies as British Petroleum, Breakout19 has a network of more than 1,500 trucks similar to transportation companies like Uber, where drivers make themselves available to be dispatched according to their health, safety and environmental requirements.

Breaker19 is doing so well, in fact, that it’s sped past Giles and Cherry’s original collaboration, BidOut.

“Breaker 19's probably, you know, growing ten times of where BidOut even was in its early days,” says Giles. “So, we'll always explore options that make sense for our shareholders. Fortunately, my co-founder and I have previous companies that we built and sold and have experience in scaling and have experiences in multiple departments, whether it be finance or sales or marketing or operations.

“So, currently, we do operate BidOut and Breaker19 separately, but they are, you know, through common operating structures. And, you know, we're able to maintain the scale and maintain the growth right now. And right now, the company is doing great financially and has cash flow positives. So, for us, you know, our goal is just to continue. I feel like we've kind of solved an archaic problem and did it in a really simple way, and it's working out pretty well.”

And it all started with a simple question from a customer — "Hey, can you guys come up with something like this?"

“It all came together just by listening to our customer’s needs,” says Giles. “And we always try to go into our clients and help them with a lot of what they do. But we always want to know about what their other pain points are. You know, there's still people, you know, that are operating with very archaic processes, very, you know, manual back-office processes. And our job is to speed them up with software. And so Breaker19 was able to do that.”

Practically speaking, Breaker19 is more than a software solution. It also closes the gap between qualified drivers and end clients by vetting participants for the platform in an efficient and pragmatic fashion.

“We have a very rigorous vetting process for the drivers,” Giles explains. “I mean, that's really what makes the oil and gas trucking industry so unique. Insurance requirements have to be significantly higher than most carriers. They have to go through very well-funded safety trainings where they are familiar with the oil field. And then number three, these drivers have to have personal protective equipment. They have to have flame-retardant clothing, they have to have slo-mo boots and they have to have hard hats.”

Procedure is important, but professionalism is equally important to Breaker19.

“You know, we do not allow the carrier to show up on a customer's locations in shorts and flip-flops or Crocs and, you know, be protected,” says Giles. “And so, for what we're dealing with is very mission critical, but also very, you know, very high-risk.

“For example, we are checking insurance statuses four times a day. If a carrier were to cancel their insurance, we're aware of it immediately because we want to make sure that we always have active insurance in place. So, we have a process that these carriers go through. Again, we've got over 1,500 of them now that are well-vetted and well-qualified.”

As Breaker19 continues to scale, Giles and Cherry hope their burgeoning app becomes the go-to ordering platform for the entire oil and gas industry for all of their trucking, hot shot and transportation needs.

“We're bringing on some significant, large enterprise clients right now that make up 10% of the U.S. market share for each customer,” says Giles “So I think when we start to compound those, I think we easily see the trajectory there as really being something that's taking off pretty fast. So, I think at the end of the day, we just hope to keep delivering a great experience for our clients, make their ordering process easy.”

With both BidOut and Breaker19 doing great financially, proud Klein Oak High School alums Giles and Cherry have purchased a steer to support Texas youth and agricultural causes. Additionally, moving forward, the duo pledges to give away a full steer each month to a customer of their Breaker19 platform.

"We are passionate about giving back to our community and nurturing the next generation of leaders in Texas," says Cherry. "Having personally experienced the transformative impact of FFA, we saw this initiative as a meaningful way to both support local agriculture and provide our clients with a taste of authentic Texas beef.”

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Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.



Rice University launches  engineering-led brain science and health institute

brain research

Rice University has announced the creation of a new interdisciplinary center known as the Rice Brain Institute (RBI).

The new hub will aim to use engineering, natural sciences and social sciences to research the brain and reduce the burden of neurodegenerative, neurodevelopmental and mental health disorders.

“The Rice Brain Institute reflects Rice’s strength in collaboration without boundaries,” Rachel Kimbro, dean of the School of Social Sciences, said in a news release. “Our researchers are not only advancing fundamental science but they’re also ensuring that knowledge reaches society in ways that promote human flourishing.”

RBI researchers will work in thematic clusters focusing on neurodegeneration, mental health, brain injury and neurodevelopment. The clusters will work toward goals such as significantly improving key brain health outcomes, reducing mortality and mental health disorders and improving quality of life for patients living with brain injuries and neurodevelopmental disorders, according to Rice.

The institute will focus on “engineering-driven innovation,” rather than traditional neuroscience, to design tools that can measure, model and modulate brain activity based around Rice’s expertise in soft robotics, neuroimaging, data science and artificial intelligence—making it unique among peer organizations, according to Rice.

Additionally, RBI will be structured around three collaborative Rice “pillars”:

  • The Neuroengineering Initiative, launched in 2018, brings together neuroscience, engineering, and related fields experts
  • The Neuroscience Initiative, a new initiative that brings together cell biologists, neurobiologists, biochemists, chemists and physicists to explore fundamental mechanisms of the brain and nervous system
  • The Brain and Society Initiative, also a new initiative, considers brain research within the broader social and policy landscape

Rice’s Neuroengineering Initiative has already garnered more than $78 million in research funding, according to Rice, and has established major partnerships, like the Rice-Houston Methodist Center for Neural Systems Restoration.

“Rice is uniquely equipped to bridge and connect scientific understanding of the brain and behavior sciences with the technologies and policies that shape our world,” Amy Dittmar, the Howard R. Hughes Provost and executive vice president for academic affairs, added in the news release. “By uniting faculty in neuroengineering, neuroscience and psychological sciences, this interdisciplinary hub embodies the kind of bold, nimble collaboration that allows Rice to turn discovery into societal impact to save lives and enhance human flourishing.”

The formation of the RBI coincides with recent support of the Dementia Prevention Research Institute of Texas (DPRIT), which landed voter approval earlier this week and aims to make Texas the center for dementia research via brain-health tech. According to the World Economic Forum, brain disorders and mental health disorders cost the global economy an estimated $5 trillion per year and could be as high as $16 trillion by 2030.

“Few areas of research have as direct and profound an impact on human well-being as brain health,” Rice President Reginald DesRoches added in the news release. “As rates of Alzheimer’s, dementia and other neurological diseases rise in our country and around the world, universities have a responsibility to lead the discovery of solutions that preserve memory, movement and quality of life. We all know someone who has been affected by a brain-related health issue, so this research is personal to all of us.”