Houston improves ranking among best U.S. cities to start a business

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Houston jumped four spots to No. 34 this year. Photo via Getty Images

Houston's reputation for being an entrepreneurial and business powerhouse was confirmed in WalletHub's new list of the "Best Large Cities to Start a Business" in 2025. The Energy Capital of the World moved up four spots this year and ranked No. 34 nationwide.

The annual report ranked 100 U.S. cities based on 19 metrics across three main categories: business environment, access to resources, and costs. Factors considered in the report include five-year business survival rates, job growth comparisons from 2019 and 2023, office space affordability, and more.

The sunny Florida city of Orlando (No. 1) topped the list as the best large city for starting a business this year.

Houston's business climate has improved slightly since 2024, when the city previously ranked No. 38.

Houston performed the best in the national business environment category, ranking No. 33 out of all 100 cities in the report. It fell behind in the categories for "business costs" and "access to resources" ranking No. 50 and No. 65, respectively.

"Starting a business can be very scary, considering one in every five startups doesn’t make it past the first year," said WalletHub analyst Chip Lupo. "That’s why it’s especially important to live in a city that provides an environment where new businesses can thrive, with enough capital, workers and customers to keep it going long-term."

Elsewhere in Texas
Austin was the only Texas city to rank among the top 10 best big cities to start a business in 2025, climbing up into the No. 3 spot.

"Businesses that are currently in Austin are thriving, as the city has a very high growth rate in the number of small businesses," the report said. "It also has the best employment growth in the country, which makes it more likely that new businesses will be able to find employees."

Dallas-Fort Worth had the greatest concentration of cities on the list, contributing six out of 13 total Texas cities, and all of them among the top 50: Fort Worth (No. 11), Arlington (No. 15), Dallas (No. 16), Irving (No. 22), Garland (No. 29), and Plano (No. 43).

Other large Texas cities that were named among the best places to start a business in 2025 include Lubbock (No. 33), Laredo (No. 44), San Antonio (No. 64), El Paso (No. 67), and Corpus Christi (No. 70).

The top 10 best large cities to start a business in 2025 are:

  • No. 1 – Orlando, Florida
  • No. 2 – Tampa, Florida
  • No. 3 – Austin, Texas
  • No. 4 – Jacksonville, Florida
  • No. 5 – Miami, Florida
  • No. 6 – St. Petersburg, Florida
  • No. 7 – Boise, Idaho
  • No. 8 – Atlanta, Georgia
  • No. 9 – Raleigh, North Carolina
  • No. 10 – Hialeah, Florida
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A version of this story originally appeared on our sister site, CultureMap.com.

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Houston made a big leap back into the top 50, ranking No. 40, after previously plummeting into No. 72 last year. Photo by Natalie Harms/InnovationMap

Houston leaps back into top 50 'World's Best Cities' list for 2025

call it a comeback

Lively Houston has regained its rightful place among the top 50 best cities in the world, according to a prestigious new report by Resonance Consultancy.

The Canada-based real estate and tourism marketing advisors ranked Houston the 40th best city worldwide for 2025 in its annual "World's Best Cities" list.

The report quantifies the relative qualities of livability, "lovability," and prosperity for the world's top 100 cities with metropolitan populations of 1 million or more. New to the 10th anniversary edition, Resonance partnered with global market researchers Ipsos to include perception-based data into the rankings, surveying over 22,000 people in 30 countries worldwide to determine "the most desirable places to visit, live or work."

Houston made a major rebound after plummeting to No. 66 in last year's report. In 2022, Houston ranked No. 42.

Resonance refers to its previous "World's Best Cities" reports and its 2024 "America's Best Cities" list – which ranked Houston in the top 10 – when explaining the Bayou City's successes. The report praised Houston's vast cultural diversity and placed a great focus on its economic prosperity, even going so far as to suggest Houston residents make more money "and can sock more away."

"...[W]here America’s fourth-largest city truly takes off is in its economic heft and wealth, ranking No. 9 globally for GDP per Capita and No. 14 for Fortune 500 companies in town," the report said. "All that rolls up into an overall Prosperity index ranking of No. 36, which is even more impressive given the No. 14-ranked Price-to Income Ratio [of the city]."

Elsewhere in Texas, Austin and Dallas also earned spots on the World's Best Cities list for 2025, but only one made a similar rebound from the previous year's rankings. Dallas moved up from No. 66 in last year's report to its current rank as No. 55. Meanwhile, Austin took its first tumble out of the 43rd spot (which it had occupied for two years straight) and now ranks No. 53.

London held onto its crown as the No. 1 best city in the world for 2025, followed by New York (No. 2), Paris (No. 3), Tokyo (No. 4), and Singapore (No. 5).

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This article originally ran on CultureMap.

Three Texas cities made the new ranking. Photo via Getty Images

Houston makes top 10 list for best US cities to start a business

best of the rest

Houston plays a historic role in launching spacecraft. But it’s also a great place to launch a business.

A new list from USA Today Blueprint puts Houston in ninth place among the best U.S. cities to start a business in 2024. Austin grabs the No. 1 spot, and Dallas sits at No. 4.

“Starting and sustaining it is a major challenge, and there are a vast number of factors that can affect your chances of success,” says USA Today Blueprint. “While the best businesses and entrepreneurs can succeed anywhere and beat any odds, it can help to think about where your business might be more likely to succeed.”

USA Today Blueprint combed through data for 46 of the country’s most popular cities to create the ranking. Houston fares especially well in two categories — business openings and growth in GDP (gross domestic product):

  • In 2021, Houston saw 16,816 business openings and 13,785 business closures, resulting in a net gain of 3,031 businesses, according to USA Today Blueprint’s analysis. The net gain gives Houston a fourth-place showing for business openings.
  • From 2021 to 2022, Houston experienced GDP growth of 14.2 percent. That was a high enough rate to earn a third-place ranking for GDP growth. Only El Paso (15 percent) and Austin (14.3 percent) notched higher rates.

“Startups in Miami, Austin, and Dallas are particularly high contributors to their city’s total employment numbers. These cities also — alongside Houston and Jacksonville — make up five of the top 10 in terms of GDP growth,” says USA Today Blueprint.

Was Houston snubbed? Photo by John Schnobrich on Unsplash

Houston falls behind other Texas cities in report ranking best tech hubs

ouch

In a recent report analyzing metrics for best cities for tech hubs, Houston failed to crack the top 20 — unlike a few other Texas cities.

The new report, "The Top Tech Cities in the US: Ranking 100 Cities in 2024," by online security experts Cloudwards, examined 100 tech-reliant cities in the nation across 17 key indicators, including salaries for information technology professionals, a city's cost of living, internet quality, job opportunities and tech-related companies, and more.

Austin is the No. 7 best tech city in the nation, yet somehow not the best in Texas; The Dallas suburb of Plano outshone the capital city at No. 4, and its neighbor Frisco came in at No. 10. Houston, however, came in at No. 22.


Courtesy of: Cloudwards.net

Here's how Houston stacked up in the major categories in the study:

  • No. 13 – Cost of Living and Tech Salaries
  • No. 16 – Career and Education
  • No. 40 – Tech Community
  • No. 44 – Innovation and Entrepreneurship
  • No. 53 – Internet Coverage and Quality

Austin's spot in No. 7 behind Plano's No. 4 might be surprising, but, according to the report, the Texas capitol's higher cost of living is to blame.

"Texas’s capital, Austin is a good place for startups since it’s easy to find top talent, initial capital and inexpensive office space," wrote the report's author. "However, due to the rapid rise in population (3 percent between 2021 and 2022), the cost of living has increased and access to good real estate has become more costly. Even so, the city’s distinct culture, access to educational opportunities and work-life balance continue to make Austin a popular choice for many IT professionals."

With many employers still embracing remote work, having a good wifi connection can make or break a person's ability to work from home. It seems that helped Plano get a leg up on Austin; 96 percent of Plano households have internet access, which was the single best connection rate of any city in the study. Austin didn't make the top five — but at least it didn't make the bottom five either.

Frisco also topped out in one category in particular, earning the title as "the most livable city in the U.S." according to Cloudwards.

Average salaries for IT professionals in Frisco come out to about $95,516 annually, which is only a $217 difference from Plano at $95,733. Given Austin's middling rank on the list above, no data was shared.

Central Texas didn't have much representation on the list. Although there were several North Texas suburbs, the only city near Austin was San Antonio, which came in at No. 18. It was the "Innovation and Entrepreneurship" category that brought it down, ranking No. 72.

Nationally, the cities that round out the top five most tech-savvy cities in the U.S. are:

  • No. 1 – New York City, New York
  • No. 2 – Washington, D.C.
  • No. 3 – San Francisco, California
  • No. 4 – Plano, Texas
  • No. 5 – Jersey City, New Jersey

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This article originally ran on CultureMap.

Six-figure earners live well in Houston. Photo via Getty Images

Report: Houston earns top-10 rank among best U.S. cities for workers making $100K

the good life

In Houston, $100,000 per year goes much farther than many other Texas cities. A new study by personal finance website GOBankingRates.com ranked Houston No. 7 on its list of the best cities for six-figure earners in the U.S.

The annual net pay after taxes for a six-figure earner in Houston comes out to $78,089, according to the study. When factoring in major expenses like rent, groceries, healthcare, utilities, transportation costs, and miscellaneous expenses, that adds up to $43,105.46 per year, which leaves just under $35,000 leftover. Houston's continuing inflation troubles surely aren't helping, either.

Here's how GOBankingRates breaks down Houston's expenses:

  • Annual rent: $19,215.67
  • Annual groceries: $5,594.64
  • Annual healthcare: $5,563.35
  • Annual utilities: $4,389.79
  • Annual transportation costs: $7,364.29
  • Annual miscellaneous costs: $977.72
Houston appears one spot lower than its No. 6-rank in a similar 2023 study by SmartAsset. That study said Houstonians' six-figure salary was reduced to $74,515 after taxes, but was technically worth $81,350 when adjusted for the cost of living.

Houston wasn't the only Texas city to earn a spot in the top 10 where a six-figure salary goes the farthest. Higher up on the list is El Paso (No. 2) and San Antonio (No. 3).

After taxes and annual expenses, six-figure earners in El Paso have $37,685 left over, which is over $2,700 more than what a Houstonian would have with the same salary. In San Antonio, residents making $100,000 per year average about $41,008 in annual expenses, which leaves $37,081 in their pockets after paying all the bills.

For the second year in a row, the U.S. city where a $100,000 salary goes the furthest is Memphis, Tennessee. Memphis residents have nearly $40,000 leftover after taxes and annual expenses on a $100,000 salary, the study says. Like Texas, Tennessee also doesn't impose an income tax on its residents.

The top 10 U.S. cities where a $100,000 salary goes the farthest are:

  • No. 1 – Memphis, Tennessee
  • No. 2 – El Paso, Texas
  • No. 3 – San Antonio, Texas
  • No. 4 – Tulsa, Oklahoma
  • No. 5 – Oklahoma City, Oklahoma
  • No. 6 – Wichita, Kansas
  • No. 7 – Houston
  • No. 8 – Tucson, Arizona
  • No. 9 – Jacksonville, Florida
  • No. 10 – Indianapolis, Indiana

In the study's analysis of the top 10 most expensive cities for six-figure earners, New York City took the crown as the city where residents are left "in the red" by the end of the year. Following close behind is San Francisco, California (No. 2); San Jose, California (No. 3); San Diego, California (No. 4); Boston, Massachusetts (No. 5); Oakland, California (No. 6); Los Angeles, California (No. 7); Washington, D.C. (No. 8); Miami, Florida (No. 9); and Long Beach, California (No. 10).

The report analyzed the average expense costs in 50 of the most populous American cities, and subtracted those costs from each city's annual net annual pay after taxes on a $100,000 salary. Rankings were determined based on the amount of annual income leftover. Data was pulled from the U.S. Census American Community Survey, the Bureau of Labor Statistics Consumer Expenditure Survey, the Zillow Observed Rental Index, and more.The report and its methodology can be found on gobankingrates.com.

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This article originally ran on CultureMap.

Houston scored high marks for food, culture, and diversity. Photo via IdeasLaboratory.com

Houston named best city in Texas and No. 11 in U.S. in prestigious report

best in tx

At least according to one new report, Houston is not only the Energy Capital of the World but also the livability capital of Texas.

A new study from Best Cities, powered by Resonance Consultancy, puts Houston at No. 11 among the best cities in the U.S. That’s the top showing among the six Texas cities included in the ranking. Houston appeared at No. 17 on last year’s list.

“Educated, diverse and hard-working, Houston is America’s stealthy powerhouse on the rise,” Best Cities proclaims.

Best Cities notes that while Austin grabs much of the best-city attention, “the promise of the Lone Star State drawing Californians and New Yorkers is quietly being fulfilled in Houston.” The website points out that the Houston metro area has gained nearly 300,000 residents in the past year, thanks to both domestic and international migration.

Here are some of the individual rankings that contribute to Houston’s 11th-place finish:

  • No. 4 for restaurants
  • No. 7 for culture
  • No. 8 for foreign-born population

“Houston is a diverse and vibrant metro where individuals can start a family, grow their business, attend world-class institutions and universities, or be immersed in the 145 languages that are spoken by our residents,” Houston Mayor Sylvester Turner says in a news release. “The quality of life we have in Houston is second to none, and the data we receive from placements such as … Best Cities further reaffirm the strength and resiliency that has come to define this great city of ours.”

A few spots behind Houston on the Best Cities list are No. 14 Dallas and No. 15 Austin.

What lifts Dallas to the No. 14 spot? These are some of the factors cited by Best Cities:

  • Location of more than 10,000 corporate headquarters
  • Strong showing (No. 2) in the airport connectivity category
  • Kudos for the soon-to-be-expanded Kay Bailey Hutchinson Convention Center Dallas
  • Home of the country’s sixth largest LGBTQ+ community
  • Presence of the 28-block, 68-acre Dallas Arts District

Austin comes in at No. 15, one notch behind Dallas.

Best Cities praises Austin as “a place that’s incredibly livable. Talk to any entrepreneur leaving Silicon Valley or Seattle and chances are they’ve considered Austin.”

The website points to a number of Austin’s assets, such as:

  • Growing presence of Fortune 500 headquarters
  • Comparatively low unemployment rate
  • Location of the University of Texas’ flagship campus
  • Status as the Live Music Capital of the World
  • Home of the annual SXSW gathering

Two other Texas cities make the Best Cities list: No. 34 San Antonio and No. 94 McAllen.

Best Cities bases its list of the best U.S. cities on Resonance Consultancy’s combination of statistical performance plus qualitative evaluations by locals and visitors. Those figures are grouped into six main categories. This year’s ranking features 100 U.S. cities. To come up with the ranking, Resonance Consultancy assessed all U.S. metro areas with at least 500,000 residents.

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This article originally ran on CultureMap.

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UH student earns prestigious award for cancer vaccine research

up-and-comer

Cole Woody, a biology major in the College of Natural Sciences and Mathematics at the University of Houston, has been awarded a Barry Goldwater Scholarship, becoming the first sophomore in UH history to earn the prestigious prize for research in natural sciences, mathematics and engineering.

Woody was recognized for his research on developing potential cancer vaccines through chimeric RNAs. The work specifically investigates how a vaccine can more aggressively target cancers.

Woody developed the MHCole Pipeline, a bioinformatic tool that predicts peptide-HLA binding affinities with nearly 100 percent improvement in data processing efficiency. The MHCole Pipeline aims to find cancer-specific targets and develop personalized vaccines. Woody is also a junior research associate at the UH Sequencing Core and works in Dr. Steven Hsesheng Lin’s lab at MD Anderson Cancer Center.

“Cole’s work ethic and dedication are unmatched,” Preethi Gunaratne, director of the UH Sequencing Core and professor of Biology & Biochemistry at NSM, said in a news release. “He consistently worked 60 to 70 hours a week, committing himself to learning new techniques and coding the MHCole pipeline.”

Woody plans to earn his MD-PhD and has been accepted into the Harvard/MIT MD-PhD Early Access to Research Training (HEART) program. According to UH, recipients of the Goldwater Scholarship often go on to win various nationally prestigious awards.

"Cole’s ability to independently design and implement such a transformative tool at such an early stage in his career demonstrates his exceptional technical acumen and creative problem-solving skills, which should go a long way towards a promising career in immuno-oncology,” Gunaratne added in the release.

Houston founder on shaping the future of medicine through biotechnology and resilience

Guest Column

Living with chronic disease has shaped my life in profound ways. My journey began in 5th grade when I was diagnosed with Scheuermann’s disease, a degenerative disc condition that kept me sidelined for an entire year. Later, I was diagnosed with hereditary neuropathy with liability to pressure palsies (HNPP), a condition that significantly impacts nerve recovery. These experiences didn’t just challenge me physically, they reshaped my perspective on healthcare — and ultimately set me on my path to entrepreneurship. What started as personal health struggles evolved into a mission to transform patient care through innovative biotechnology.

A defining part of living with these conditions was the diagnostic process. I underwent nerve tests that involved electrical shocks to my hands and arms — without anesthesia — to measure nerve activity. The pain was intense, and each test left me thinking: There has to be a better way. Even in those difficult moments, I found myself thinking about how to improve the tools and processes used in healthcare.

HNPP, in particular, has been a frustrating condition. For most people, sleeping on an arm might cause temporary numbness that disappears in an hour. For me, that same numbness can last six months. Even more debilitating is the loss of strength and fine motor skills. Living with this reality forced me to take an active role in understanding my health and seeking solutions, a mindset that would later shape my approach to leadership.

Growing up in Houston, I was surrounded by innovation. My grandfather, a pioneering urologist, was among the first to introduce kidney dialysis in the city in the 1950s. His dedication to advancing patient care initially inspired me to pursue medicine. Though my path eventually led me to healthcare administration and eventually biotech, his influence instilled in me a lifelong commitment to medicine and making a difference.

Houston’s thriving medical and entrepreneurial ecosystems played a critical role in my journey. The city’s culture of innovation and collaboration provided opportunities to explore solutions to unmet medical needs. When I transitioned from healthcare administration to founding biotech companies, I drew on the same resilience I had developed while managing my own health challenges.

My experience with chronic disease also shaped my leadership philosophy. Rather than accepting diagnoses passively, I took a proactive approach questioning assumptions, collaborating with experts, and seeking new solutions. These same principles now guide decision-making at FibroBiologics, where we are committed to developing groundbreaking therapies that go beyond symptom management to address the root causes of disease.

The resilience I built through my health struggles has been invaluable in navigating business challenges. While my early career in healthcare administration provided industry insights, launching and leading companies required the same determination I had relied on in my personal health journey.

I believe the future of healthcare lies in curative treatments, not just symptom management. Fibroblast cells hold the promise of engaging the body’s own healing processes — the most powerful cure for chronic diseases. Cell therapy represents both a scientific breakthrough and a significant business opportunity, one that has the potential to improve patient outcomes while reducing long-term healthcare costs.

Innovation in medicine isn’t just about technology; it’s about reimagining what’s possible. The future of healthcare is being written today. At FibroBiologics, our mission is driven by more than just financial success. We are focused on making a meaningful impact on patients’ lives, and this purpose-driven approach helps attract talent, engage stakeholders, and differentiate in the marketplace. Aligning business goals with patient needs isn’t just the right thing to do, it’s a powerful model for sustainable growth and lasting innovation in biotech.

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Pete O’Heeron is the CEO and founder of FibroBiologics, a Houston-based regenerative medicine company.


Houston researchers make headway on affordable, sustainable sodium-ion battery

Energy Solutions

A new study by researchers from Rice University’s Department of Materials Science and NanoEngineering, Baylor University and the Indian Institute of Science Education and Research Thiruvananthapuram has introduced a solution that could help develop more affordable and sustainable sodium-ion batteries.

The findings were recently published in the journal Advanced Functional Materials.

The team worked with tiny cone- and disc-shaped carbon materials from oil and gas industry byproducts with a pure graphitic structure. The forms allow for more efficient energy storage with larger sodium and potassium ions, which is a challenge for anodes in battery research. Sodium and potassium are more widely available and cheaper than lithium.

“For years, we’ve known that sodium and potassium are attractive alternatives to lithium,” Pulickel Ajayan, the Benjamin M. and Mary Greenwood Anderson Professor of Engineering at Rice, said in a news release. “But the challenge has always been finding carbon-based anode materials that can store these larger ions efficiently.”

Lithium-ion batteries traditionally rely on graphite as an anode material. However, traditional graphite structures cannot efficiently store sodium or potassium energy, since the atoms are too big and interactions become too complex to slide in and out of graphite’s layers. The cone and disc structures “offer curvature and spacing that welcome sodium and potassium ions without the need for chemical doping (the process of intentionally adding small amounts of specific atoms or molecules to change its properties) or other artificial modifications,” according to the study.

“This is one of the first clear demonstrations of sodium-ion intercalation in pure graphitic materials with such stability,” Atin Pramanik, first author of the study and a postdoctoral associate in Ajayan’s lab, said in the release. “It challenges the belief that pure graphite can’t work with sodium.”

In lab tests, the carbon cones and discs stored about 230 milliamp-hours of charge per gram (mAh/g) by using sodium ions. They still held 151 mAh/g even after 2,000 fast charging cycles. They also worked with potassium-ion batteries.

“We believe this discovery opens up a new design space for battery anodes,” Ajayan added in the release. “Instead of changing the chemistry, we’re changing the shape, and that’s proving to be just as interesting.”

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This story originally appeared on EnergyCapitalHTX.com.

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