2 Houston startups make strategic hires

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Two Houstonians have been named to the C-suites of growing startups. Photos courtesy

A pair of Houston tech startups have recently announced new appointments to their leadership staff. A digital supply chain commerce company named a new CFO, while an Irish health tech company has named its new Houston-based leader.

GoExpedi names new CFO

Jorge Ordonez is the newly named CFO for GoExpedi. Photo courtesy of GoExpedi

Houston-based GoExpedi, an innovative end-to-end digital supply chain and data analytics solutions company, named Jorge Ordonez as CFO for the company.

"With our rapidly accelerating growth, ongoing investment activity and new industrial customers coming online, it was crucial that we bring on board an experienced financial leader who can help us successfully scale at a fast pace," says Tim Neal, GoExpedi CEO, in a news release. "Jorge led one of the top medical equipment providers in the country as well as a leading industrial technology solutions provider. We'll greatly benefit from his diverse financial experience, helping us to become the leading digital industrial supply chain and data analytics providers in North America."

Ordonez brings 25 years of finance and accounting experience across industries, including 10 years in distribution and logistics. His most recent position was CFO at US Med-Equip, a medical equipment provider.

"I am honored to join GoExpedi, one of the most innovative industrial supply chain and data solutions providers out there, at this time of rapid growth," says Ordonez in the release. "I look forward to working closely with GoExpedi's leadership team to support sustained financial success as the company expands into different geographies and sectors. My goals are to help the company continue its financial success and build optimized financial decision-making models and processes that will equip the company to scale and expand capital availability to continue its growth trajectory."

Health tech startup with US operations in Houston names new CEO

Benjamin A. Hertzog will lead Intelligent Implants through its next phase of development. Photo courtesy of Intelligent Implants

Benjamin A. Hertzog, entrepreneur in residence at Johnson and Johnson’s Center for Device Innovation at the Texas Medical Center, has a new title. Last month, Hertzog was named CEO of Intelligent Implants, a development-stage digital medicine and orthopedics startup based in Ireland with its United States operations based in Houston.

“Ben joined Intelligent Implants as Executive Chairman of the Board in 2020, and his broad experience in complex Class-III medical devices, leadership, and exceptional track record made it an obvious choice to have Ben join us at the helm of the company,” says John Zellmer, Intelligent Implants co-founder and founding CEO, in a news release. “Ben has the skills and credibility to guide Intelligent Implants as we navigate through the next stage of clinical and commercial activities. We look forward to his leadership as we continue to achieve key milestones.”

Zellmer will transition into the role of COO while Hertzog is tasked with leading product development, as well as clinical, and commercial activities for the company’s novel and proprietary smart orthopedic implant platform.

With more than 20 years of experience in healthcare and life sciences as an engineer, investor, and entrepreneur, Hertzog has founded medical device startup, Procyrion, leading the cardiac device company through Series C financing, product development, animal studies, strategic investment, and human clinical trials. He also served as managing director of AlphaDev (now Fannin Partners), an early-stage venture development firm.

“I am thrilled to work with John and the entire Intelligent Implants team as we make progress towards bringing this novel technology platform to the market,” says Hertzog. “Throughout my career, I’ve been driven by and focused on bringing innovative medical device therapies to the market, and I believe that SmartFuse represents the future of medical devices; smart connected implants that provide therapeutic benefits and real-time data to support clinical decision making. Ultimately, I believe these implants will have significant advantages to traditional implants in addressing unmet clinical needs and improving patient outcomes.”

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.

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