Houston-born Matt Mullenweg joined the Greater Houston Partnership for a fireside chat on his tech company Automattic's success of distributed work. Photo via ma.tt

The pandemic and the measures companies have taken to prevent the spread of COVID-19 have opened employers eyes to non-traditional ways of working. An increased percentage of the workforce pivoted to remote working this year — in some cases, this was the first time employees were allowed to work from home.

But not having a traditional office setup is far from new to Houston native Matt Mullenweg, founder of WordPress. He started his company with remote team members basically from day one. In a virtual fireside chat with Scott McClelland, president of H-E-B Food & Drug, for Greater Houston Partnership's Houston NEXT: An ERG Summit last month, Mullenweg describes why he feels confident that a remote — or distributed, has he defines it — workforce is the future.

"Words are really important, and when I hear the word 'remote,' I think there's a central office and then there's someone who's not part of it," Mullenweg says during the chat. "So, we were trying to think of something that captured the fact that we were close to each other in our work — we're just not physically in the same place most of the time. 'Distributed' is what we came up with."

For Mullenweg, this way of running his business was advantageous for the company at its founding in 2000. Since those early days, Automattic, WordPress's parent company, has raised around $700 million in venture funding and made around 20 acquisitions. This success, Mullenweg says, is in part due to distributed work.

"All of this is designed to create a really robust network so that the work can continue regardless of location or anything," Mullenweg says on his workforce structure. "This especially during the early days, allowed us to work two or three times faster than our competitors because when they were doing five days of work a week, we were doing 15 days of work a week."

Mullenweg's plan for distributed work has been the subject a series of blogs, a podcast, and even a TED Talk. As passionate as he is that it is the future of the workforce, he realizes there's a process to getting there, and it's going to take time. He explains a five-tiered process that focuses on strategic culture changes and tech optimization.

"I think you need to have a culture and a way of working that allows people who aren't physical co-present with their colleagues to be productive," Mullenweg says. "The truth is not every company is there yet."

While Mullenweg always believed the rise of distributed work would reach milestones throughout his lifetime, the pandemic might be accelerating crucial steps toward the growth of this type of workforce. Especially since, as Mullenweg explains, this isn't the last major event that's going to occur and prevent in-person work.

"We're all hoping COVID to be gone as soon as possible, but this isn't the last thing like this. I'm sure there are going to be other issues that require us to be more decentralized in the future," Mullenweg says. "If you can get good at that as an organization, you'll be primed to succeed in the coming decades as a business."

Ultimately, distributed work has a lot of potential in the modern workforce, and the structure can do wonders for business advancement as well as employee moral.

"One thing we've found is that when people are really happy and fulfilled, they bring their best selves to work — they're more creative and have more energy," Mullenweg says.

Houston NEXT: An ERG Summit - Fireside Chat with Matt Mullenwegwww.youtube.com

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.