Autio partnered with the Texas State Historical Association to bring more than 1,000 stories to the app over the next year. Photo by freddie marriage on Unsplash

There's almost no better education on the state of Texas than driving through it — almost. The only thing better would be listening to stories about Texas history on that drive.

A GPS-based entertainment app, Autio (currently only available to iPhone users), has Texas road trippers covered thanks to a partnership with the Texas State Historical Association (TSHA), bringing more than 1,000 stories to car speakers in the Lone Star State over the next year.

“Our partnership with Texas State Historical Association allows listeners to immerse themselves in theTexas history and culture — whether they’re driving through on a road trip with their family, locals on a hike interested in learning more about their homeland, or simply someone who is interested in history,” said Woody Sears, CEO, and co-founder at Autio. “We’re thrilled to be expanding our portfolio on Autio and to provide listeners with the unique stories that TSHA has in their impressive library.”

Autio, founded in part by actor Kevin Costner, who helps narrate stories alongside Phil Jackson, John Lithgow, and other readers, works like a giant self-guided tour. As app users approach an area with a story attached, they receive notifications that a story is available, giving interesting historical context to a region or even pointing out unique places to stop on the way.

Similar apps have helped users explore Austin with fun missions and geocaching opportunities, but Autio covers the United States. There are not separate tracks for different regions, making it a seamless experience no matter where a trip leads — although there will be lots of quiet time. Each story is only a few minutes long.

The library of Texas stories features historical moments, landmarks, and notable individuals in more than 100 cities. There are already hundreds of stories to browse, including one in Austin about Barbara Conrad, a Black opera singer who drew attention to the University of Texas in 1957 when she was removed from a role that placed her in an onstage romance with a white performer.

There are at least 13 stories in Austin, depending on how you define the area. The topics are mostly about natural areas and politics (it is the capital, after all). Nearby stories highlight the Bee Cave Sculpture Park, the early history of Bastrop, the Round Rock philanthropist D.H. Snyder, and the nomadic people that founded Pinta Trail near Fredericksburg.

Houston has the most stories in Texas, followed by the DFW and then San Antonio, all with more than 75 unique tales. A map shows an even distribution of stories across the state that include some often-overlooked areas with quotes from Lonesome Dove, explanations of rural legends, and overviews of small, but notable towns.

“Autio’s unique mission ... perfectly aligns with our purpose to foster an appreciation for the unique history of Texas,” said Dr. Brett Derbes, the managing editor for Handbook of Texas, a digital encyclopedia managed by TSHA. “We’re excited to see this partnership come to fruition and continue to educate more and more people on the great state we get to call home.”

Listeners can tune in for a seven-day free trial through TSHA, using the code TSHA_TRY7. New TSHA members receive an additional $10 off in the Autio app ($29.99 for 30 days, or $35.99 for the year). More information is available at autio.com.

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This article originally ran on CultureMap.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.