Houston's Intuitive Machines aims to launch a lander in mid-February, hopping a flight with SpaceX. Photo via intuitivemachines.com

China and India scored moon landings, while Russia, Japan and Israel ended up in the lunar trash heap. Now two private companies are hustling to get the U.S. back in the game, more than five decades after the Apollo program ended — and one is based in Space City Houston.

It’s part of a NASA-supported effort to kick-start commercial moon deliveries, as the space agency focuses on getting astronauts back there.

“They’re scouts going to the moon ahead of us," said NASA Administrator Bill Nelson.

Pittsburgh's Astrobotic Technology is up first with a planned liftoff of a lander today aboard a brand new rocket, United Launch Alliance’s Vulcan. Houston's Intuitive Machines aims to launch a lander in mid-February, hopping a flight with SpaceX.

Then there's Japan, which will attempt to land in two weeks. The Japanese Space Agency’s lander with two toy-size rovers had a big head start, sharing a September launch with an X-ray telescope that stayed behind in orbit around Earth.

If successful, Japan will become the fifth country to pull off a lunar landing. Russia and the U.S. did it repeatedly in the 1960s and 70s. China has landed three times in the past decade — including on the moon’s far side — and is returning to the far side later this year to bring back lunar samples. And just last summer, India did it. Only the U.S. has put astronauts on the moon.

Landing without wrecking is no easy feat. There's hardly any atmosphere to slow spacecraft, and parachutes obviously won't work. That means a lander must descend using thrusters, while navigating past treacherous cliffs and craters.

A Japanese millionaire’s company, ispace, saw its lander smash into the moon last April, followed by Russia’s crash landing in August. India triumphed a few days later near the south polar region; it was the country’s second try after crashing in 2019. An Israeli nonprofit also slammed into the moon in 2019.

The United States has not attempted a moon landing since Apollo 17’s Gene Cernan and Harrison Schmitt, the last of 12 moonwalkers, explored the gray, dusty surface in December 1972. Mars beckoned and the moon receded in NASA's rearview mirror, as the space race between the U.S. and the Soviet Union came to a close. The U.S. followed with a handful or two of lunar satellites, but no controlled landers — until now.

Not only are Astrobotic and Intuitive Machines looking to end America’s moon-landing drought, they’re vying for bragging rights as the first private entity to land — gently — on the moon.

Despite its later start, Intuitive Machines has a faster, more direct shot and should land within a week of liftoff. It will take Astrobotic two weeks just to get to the moon and another month in lunar orbit, before a landing is attempted on Feb. 23.

If there are rocket delays, which already have stalled both missions, either company could wind up there first.

“It’s going to be a wild, wild ride,” promised Astrobotic’s chief executive John Thornton.

His counterpart at Intuitive Machines, Steve Altemus, said the space race is "more about the geopolitics, where China is going, where the rest of the world’s going.” That said, “We sure would like to be first.”

The two companies have been nose to nose since receiving nearly $80 million each in 2019 under a NASA program to develop lunar delivery services. Fourteen companies are now under contract by NASA.

Astrobotic’s four-legged, 6-foot-tall (1.9-meter-tall) lander, named Peregrine after the fastest bird, a falcon, will carry 20 research packages to the moon for seven countries, including five for NASA and a shoebox-sized rover for Carnegie Mellon University. Peregrine will aim for the mid-latitudes' Sinus Viscositatis, or Bay of Stickiness, named after the long-ago silica magma that formed the nearby Gruithuisen Domes.

Intuitive Machines’ six-legged, 14-foot-tall (4-meter-tall) lander, Nova-C, will target the moon’s south polar region, also carrying five experiments for NASA that will last about two weeks. The company is targeting 80 degrees south latitude for touchdown. That would be well within Antarctica on Earth, Altemus noted, and 10 degrees closer to the pole than India landed last summer.

Scientists believe the south pole’s permanently shadowed craters hold billions of pounds (kilograms) of frozen water that could be used for drinking and making rocket fuel. That’s why the first moonwalkers in NASA’s Artemis program — named after Apollo’s twin sister in Greek mythology — will land there. NASA still has 2025 on the books for that launch, but the General Accountability Office suspects it will be closer to 2027.

Astrobotic will head to the south pole on its second flight, carrying NASA’s water-seeking Viper rover. And Intuitive Machines will return there on its second mission, delivering an ice drill for NASA.

Landing near the moon’s south pole is particularly dicey.

“It’s so rocky and craggy and full of craters at the south pole and mountainous, that it’s very difficult to find a lighted region to touch down safely," Altemus said. "So you’ve got to be able to finesse that and just set it down right in the right spot.”

While Houston has long been associated with space, Pittsburgh is a newcomer. To commemorate the Steel City, Astrobotic’s lander will carry a Kennywood amusement park token, the winner of a public vote that beat out the Steelers’ Terrible Towel waved at football games, dirt from Moon Township’s Moon Park, and a Heinz pickle pin.

The lander is also carrying the ashes or DNA from 70 people, including “Star Trek” creator Gene Roddenberry and science fiction writer Arthur C. Clarke. Another 265 people will be represented on the rocket’s upper stage, which will circle the sun once separated from the lander. They include three original “Star Trek” cast members, as well as strands of hair from three U.S. presidents: George Washington, Dwight D. Eisenhower and John F. Kennedy.

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5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.



Rice University launches  engineering-led brain science and health institute

brain research

Rice University has announced the creation of a new interdisciplinary center known as the Rice Brain Institute (RBI).

The new hub will aim to use engineering, natural sciences and social sciences to research the brain and reduce the burden of neurodegenerative, neurodevelopmental and mental health disorders.

“The Rice Brain Institute reflects Rice’s strength in collaboration without boundaries,” Rachel Kimbro, dean of the School of Social Sciences, said in a news release. “Our researchers are not only advancing fundamental science but they’re also ensuring that knowledge reaches society in ways that promote human flourishing.”

RBI researchers will work in thematic clusters focusing on neurodegeneration, mental health, brain injury and neurodevelopment. The clusters will work toward goals such as significantly improving key brain health outcomes, reducing mortality and mental health disorders and improving quality of life for patients living with brain injuries and neurodevelopmental disorders, according to Rice.

The institute will focus on “engineering-driven innovation,” rather than traditional neuroscience, to design tools that can measure, model and modulate brain activity based around Rice’s expertise in soft robotics, neuroimaging, data science and artificial intelligence—making it unique among peer organizations, according to Rice.

Additionally, RBI will be structured around three collaborative Rice “pillars”:

  • The Neuroengineering Initiative, launched in 2018, brings together neuroscience, engineering, and related fields experts
  • The Neuroscience Initiative, a new initiative that brings together cell biologists, neurobiologists, biochemists, chemists and physicists to explore fundamental mechanisms of the brain and nervous system
  • The Brain and Society Initiative, also a new initiative, considers brain research within the broader social and policy landscape

Rice’s Neuroengineering Initiative has already garnered more than $78 million in research funding, according to Rice, and has established major partnerships, like the Rice-Houston Methodist Center for Neural Systems Restoration.

“Rice is uniquely equipped to bridge and connect scientific understanding of the brain and behavior sciences with the technologies and policies that shape our world,” Amy Dittmar, the Howard R. Hughes Provost and executive vice president for academic affairs, added in the news release. “By uniting faculty in neuroengineering, neuroscience and psychological sciences, this interdisciplinary hub embodies the kind of bold, nimble collaboration that allows Rice to turn discovery into societal impact to save lives and enhance human flourishing.”

The formation of the RBI coincides with recent support of the Dementia Prevention Research Institute of Texas (DPRIT), which landed voter approval earlier this week and aims to make Texas the center for dementia research via brain-health tech. According to the World Economic Forum, brain disorders and mental health disorders cost the global economy an estimated $5 trillion per year and could be as high as $16 trillion by 2030.

“Few areas of research have as direct and profound an impact on human well-being as brain health,” Rice President Reginald DesRoches added in the news release. “As rates of Alzheimer’s, dementia and other neurological diseases rise in our country and around the world, universities have a responsibility to lead the discovery of solutions that preserve memory, movement and quality of life. We all know someone who has been affected by a brain-related health issue, so this research is personal to all of us.”

Texas voters OK $3 billion for new dementia research institute

state funding

Texas voters on Nov. 4 overwhelmingly approved a ballot measure that provides $3 billion in state funding over a 10-year span for the newly established Dementia Prevention and Research Institute of Texas (DPRIT).

Thanks to the passage of Proposition 14, Texas now boasts the country’s largest state-funded initiative dedicated to dementia research and prevention, according to the Alzheimer’s Association. Up to $300 million in grants will be awarded during the 10-year funding period.

“This is a transformative moment for Texas and for the fight against Alzheimer’s and all other dementia,” said Joanne Pike, president and CEO of the Alzheimer’s Association. “Texans have chosen to invest in hope, innovation, and solutions for the millions of families affected by these devastating diseases. With the passage of Proposition 14, Texas is now poised to lead the nation in dementia research and prevention.”

The association says DPRIT will drive scientific breakthroughs, attract top-notch dementia researchers to Texas, and generate thousands of jobs statewide.

An estimated 460,000 Texans are living with dementia, the association says, and more than one million caregivers support them.

DPRIT is modeled after the Cancer Prevention and Research Institute of Texas (CPRIT). Since 2008, the state agency has awarded nearly $4 billion in grants to research organizations for cancer-related academic research, prevention programs, and product development.

An analysis by the McKinsey Health Institute found that investing in brain health initiatives like DPRIT could boost Texas’ GDP by $260 billion. Much of that GDP bump could benefit the Houston area, which is home to dementia-focused organizations such as UTHealth Houston Neurosciences, Baylor College of Medicine’s Center for Alzheimer’s and Neurodegenerative Diseases, the University of Texas Medical Branch at Galveston’s Collaborative Alzheimer’s Disease and Memory Disorders Program, and the Houston Methodist Research Institute’s John M. O’Quinn Foundation Neurodegenerative Disorders Laboratory.

The Greater Houston Partnership says DPRIT holds the potential “to elevate Texas — particularly Houston — as a hub for brain health research.”

State Sen. Joan Huffman, a Houston Republican, is one of DPRIT’s champions. She sponsored legislation this year to create the institute and ask Texas voters to approve the $3 billion in funding.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said in May. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our health care community.”