Houston-based Archaea Energy's RNG facilities capture waste emissions and convert them into low-carbon fuel. Photo via archaeaenergy.com

BP’s proposed $4.1 billion acquisition of Houston-based Archaea Energy promises to dramatically boost the energy giant’s presence in the biogas market.

Publicly traded Archaea is one of the largest producers of renewable natural gas, or RNG, in the U.S. Its RNG facilities capture waste emissions and convert them into low-carbon fuel. Biogas is produced through the conversion of organic matter like animal manure, trash, plant material, food waste, and sewage.

Through the cash-and-debt deal, BP will gain ownership of 50 RNG and landfill gas-to-energy facilities across the U.S. Once the deal is wrapped up, BP anticipates a 50 percent increase in biogas volumes.

Archaea's development pipeline of more than 80 projects holds the potential for a fivefold increase in RNG volumes at BP by 2030. The pipeline includes 40 RNG projects that Archaea plans to develop with Republic Services, a solid waste disposal company based in Phoenix. Republic Services is a rival of Houston-based Waste Management.

BP expects Archaea to double its biogas-driven EBITDA to about $2 billion within the next eight years. Allied Market Research predicts the global market for waste-derived biogas will jump from $52.9 billion in 2020 to $126.2 by 2030.

The Archaea acquisition is set to close later this year. Once the deal is completed, Archaea will operate as subsidiary of BP, whose U.S. headquarters is in Houston. Archaea relocated its headquarters from Pittsburgh to Houston last year.

“Archaea was founded with a mission to build the world’s leading RNG development company to reduce global emissions and make multigenerational sustainability impacts,” Nick Stork, co-founder and CEO of Archaea, says in a news release. “In a very short period of time, we have rapidly become a leading RNG platform in the U.S., and [the BP acquisition] will further enable this business to realize its full potential.”

BP notes that the demand for biogas is rising thanks to the growth of renewable hydrogen, electric-vehicle charging, and other emerging segments of the energy sector.

“Our biogas team is already one of the leading suppliers of renewable natural gas in North America,” Dave Lawler, chairman and president of BP America, says in a news release. “This deal accelerates our ability to deliver cleaner energy, generate significant earnings in a fast-growing sector, and help reduce emissions. This could help BP take a significant stride toward our net-zero ambition.”

BP America employs nearly 4,000 full-time workers in Houston.

More than half of non-Texans think the Lone Star State is great for business. Photo via Getty Images

Here's what non-Texans think about the Lone Star State's business economy

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As Houston and the rest of Texas continue to welcome out-of-state businesses, there’s some affirming news from a new poll. More than half of non-Texans believe the Lone Star State is a good place to launch a business.

The survey, conducted earlier this summer by Austin-based Crosswinds Media & Public Relations and Asbury Park, New Jersey-based Rasmussen Reports, a conservative-leaning polling company, found 53 percent of non-Texans had a positive perception of Texas as a place to do business. Only 23 percent of adults outside Texas had a “bad” or “very bad” view of the state’s business environment, while 24 percent said they were unsure.

The survey questioned 845 American adults who don’t live in Texas.

Thomas Graham, president and CEO of Crosswinds, says the survey results demonstrate that “the brand of the Lone Star State remains strong.”

In recent years, a number of out-of-state companies have been lured by that brand as well as the business climate in Houston. Notable examples include Hewlett Packard Enterprise, NRG Energy, and Axiom Space.

Just this year, several companies based outside Texas have revealed headquarters moves to the Houston area. Among them are:

  • Archaea Energy, which was based in Pittsburgh. The company produces renewable natural gas.
  • CDI Engineering Solutions, which was based in Philadelphia. The company provides engineering and architecture services.
  • DarkPulse, which was based in New York City. The company develops fiber-sensor technology.
  • Noodoe EV, which was based in Irvine, California. The company’s cloud-based platform manages charging stations for electric vehicles.

Jennifer Chang, CEO of Noodoe, says her company relocated its headquarters from Southern California to Texas to take advantage of Houston’s central location.

“Houston has the port and airport capacity we need to efficiently meet the unprecedented demand for EV charging stations,” Chang said in a January news release. “Houston has long been the Energy Capital of the World, mostly because of oil and gas extraction. Noodoe will help the city continue its energy legacy, only this time without fossil fuels.”

The poll from Crosswinds and Rasmussen was completed around the same time that CNBC released its ranking of the best states for doing business. Texas landed in fifth place, down one notch from its perch in CNBC’s 2021 study. A day later, CNBC put out a list of the worst states to live, with Texas appearing at No. 2 behind Arizona.

CNBC notes that skilled workers are flooding Texas, even though the quality of life here raises questions. The new arrivals “are finding limited childcare options, a stressed health care system with the highest rate of uninsured, new curbs on voting rights, and few protections against discrimination,” the cable TV network declares.

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New Houston biotech co. developing capsules for hard-to-treat tumors

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Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

Microsoft partners with Rice University's OpenStax on AI teaching tool

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Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”