Houston tech co. to build powerful supercomputer to help reach net-zero goals

big upgrade

The new supercomputer is expected to be one of the world’s most powerful owned by an enterprise. Photo courtesy of HPE

A Houston tech company is building a next-generation supercomputer for one of the world’s largest energy providers.

Hewlett Packard Enterprise announced its plans to build HPC6 for Italian energy company Eni. Eni will use the system to advance scientific discovery and engineering toward accelerating innovation in energy transition to help aid its goal in getting to net zero. HPC6 is expected to be one of the world’s most powerful supercomputers owned by an enterprise.

HPC6 will be built with the same innovations that power the world’s fastest supercomputer to support data and image-intensive workloads across artificial intelligence, modeling, and simulation. According to a news release from HPE, the system will “augment Eni’s existing research that is focused on studying and identifying new energy sources, including renewable energy.”

Eni’s HPC6 will be installed in the company’s energy Green Data Center in Italy. The center will be upgraded to support HPE’s direct liquid-cooling (DLC) capabilities.

"Businesses are finding themselves balancing the huge business opportunities enabled by their AI investments with the responsibility of mitigating the environmental impact of these powerful systems," Antonio Neri, president and CEO of HPE, says in a news release.

"As the leader in developing energy efficient AI and supercomputing solutions, HPE is uniquely positioned to help organizations minimize power consumption while maximizing business outcomes," he continues. "We are excited to play a role in Eni’s commitment to decarbonization supported by digitalization and innovation."

Originally announced in 2020, HPE moved its headquarters to Houston in 2022.

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This article originally ran on EnergyCapital.

The transaction, which was approved by both companies' boards, is expected to close either later this year or early next year. Photo courtesy of HPE

Houston-based HPE to acquire cloud infrastructure co. in $14B deal

M&A moves

Hewlett Packard Enterprise is buying Juniper Networks in an all-cash deal valued at about $14 billion, which is anticipated to double HPE's networking business.

Shares of both companies rose before the market open on Wednesday. A Wall Street Journal report about a potential deal saw Juniper's stock surge 22 percent and HPE's stock dip 9 percent before an official announcement was made.

HPE will pay $40 per Juniper share.

Juniper, based in Sunnyvale, California, helps companies access the cloud infrastructure that serves as the foundation of digital and AI strategies.

“This transaction will strengthen HPE’s position at the nexus of accelerating macro-AI trends, expand our total addressable market, and drive further innovation for customers as we help bridge the AI-native and cloud-native worlds, while also generating significant value for shareholders," HPE President and CEO Antonio Neri said late Tuesday in a statement.

Juniper CEO Rami Rahim will lead the combined HPE networking business. He will report to Neri. HPE was spun off from Hewlett-Packard, one of the founding companies of Silicon Valley, in 2015 and is now based in Houston.

The transaction, which was approved by both companies' boards, is expected to close either later this year or early next year. It still needs approval from Juniper shareholders and regulators.

Last March, HPE announced its plans to acquire OpsRamp, a software-as-a-service company with an IT operations management, or ITOM, platform that can monitor, automate, and manage IT infrastructure, cloud resources, and more.

Hewlett Packard Enterprise's new Houston-area facility will open in 2022. Photo courtesy of HPE/GHP

Tech giant Hewlett Packard Enterprise taps Houston area for global headquarters relocation

here comes HPE

Thousands of potential jobs are coming to the Bayou City region with a major move by a Fortune 500 company. Hewlett Packard Enterprise (HPE) and Texas Gov. Greg Abbott have announced that HPE will relocate its global headquarters to Spring, Texas from San Jose, California.

The headquarters will be located in a new state-of-the-art campus that will open in early 2022, and will build on the company's established presence in the state of Texas, according to a press release. The new campus, being built in the 60-acre Springwoods Village development, will consist of two five-story buildings with some 440,000 square feet of combined space. HPE already boasts a significant footprint in the Houston region, with more than 2,600 area employees, the Greater Houston Partnership notes.

HPE cited Houston's diverse talent base and low cost of doing business as key factors driving the move to the digital tech hub and global headquarters city.

A global enterprise information technology company that helps customers drive digital transformation by "unlocking value from all of their data," HPE delivers unique, open, and intelligent technology solutions, per the GHP. It works to create a consistent experience across all clouds and edges, to help customers develop new business models, engage in new ways, and increase operational performance. HPE has a long Houston pedigree, as Hewlett Packard merged with Compaq Computers in 2002. The company was founded in 2015 following the separation from HP, Inc., and is currently ranked 109 on the list of Fortune 500 companies.

Texas is already the site of HPE locations in Austin, Plano, and Houston. It currently operates major product development, services, manufacturing, and lab facilities in Houston and Austin.

The Houston move would no doubt be a boon to the local economy and create myriad jobs in the sector.

"As we look to the future, our business needs, opportunities for cost savings, and team members' preferences about the future of work, we are excited to relocate HPE's headquarters to the Houston region," said Antonio Neri, CEO of HPE, in a release. "Houston is an attractive market to recruit and retain future diverse talent and where we are currently constructing a state-of-the-art new campus. We look forward to continuing to expand our strong presence in the market."

Abbott applauded the move in a statement, noting, "We are excited that Hewlett Packard Enterprise has chosen to call Texas home, and I thank them for expanding their investment in the Lone Star State by relocating their headquarters to the Houston region. Hewlett Packard Enterprise joins more than 50 Fortune 500 companies headquartered in the Lone Star State, including 22 in the Houston area alone. That is because Texas offers the best business climate in the nation. Our low taxes, high quality of life, top-notch workforce, and tier one universities create an environment where innovative companies like HPE can flourish. We look forward to a successful partnership with HPE, as together we build a more prosperous future for Texas."

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This article originally ran on CultureMap.

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Rice University launches new venture fund for university-affiliated startups

startup support

Rice University has launched its new One Giant Leap Ventures Fund I, which will invest in the university’s spinouts and alumni-founded startups.

The early-stage institutional venture fund will function with a hybrid structure that allows for participation from traditional equity investors and philanthropic investors. According to the university, the fund will invest up to $500,000 per Rice-affiliated company.

To be considered eligible for funds, companies must use intellectual property licensed by the university or be led or founded by alumni.

One Giant Leap will draw on support and mentorship from Rice’s pool of 60,000 alumni and aims to create educational opportunities within the investment phases, work with graduate and undergraduate venture students, explore the scaling and commercialization of their ideas, and help investigate all the facets of venture capital.

“Rice alumni bring an extraordinary depth of experience as entrepreneurs, investors and industry leaders, and One Giant Leap creates new ways to put that expertise to work for the next generation of Rice innovators,” Stephen Bayer, vice president for development and alumni relations, said in a news release. “It strengthens the connection between our alumni and the university while giving them meaningful opportunities to mentor, advise and support Rice-affiliated companies as they grow.”

The fund held its first close in August and made its first investment into Rice brain health spinout Motif Neurotech. Led by Rice faculty member Jacob Robinson, Motif is working to commercialize a minimally invasive neurostimulator that targets treatment-resistant depression. In May, the FDA approved the company to move forward with its first clinical trial.

“Research produces breakthrough technologies and our academic environment forms outstanding entrepreneurs,” said Adrian Trömel, the fund’s managing director, a Rice alumnus and a startup founder who also serves as Rice’s interim chief innovation officer.

One Giant Leap joins the already long list of Rice-led programs that foster innovation, including the Liu Idea Labs for Innovation and Entrepreneurship’s Innovation Fellows and Summer Venture Studio, the Rice Alliance’s Business Plan Competition, the Ion District, Woodside Rice Decarbonization Accelerator, Rice Nexus, the Biotech Launchpad and RBL Ventures and its upcoming 200,000 square-foot research lab the Arc.

“With One Giant Leap, I am excited that we are creating a unique structure that brings together traditional investment and philanthropic participation to invest in and help catalyze our startups, engage the deep expertise within the Rice ecosystem and transform those strengths into real-world impact,” Trömel added in the release.

New statewide plan aims to eliminate cervical cancer in Texas by 2032

fighting cancer

MD Anderson, on behalf of a coalition of health systems, has announced a new plan to eliminate cervical cancer in Texas.

The five-year Texas Lone Star Cervical Cancer Elimination Plan was launched during the Cancer Prevention and Research Institute of Texas (CPRIT) 2026 Innovations Conference in Galveston this month.

The plan focuses on three major pillars with goals to be achieved by 2032:

  • HPV vaccination: Increase the percentage of Texas boys and girls up to date on human papillomavirus (HPV) vaccination by age 15 from 50.5 percent to 80 percent
  • Cervical cancer screening: Raise the share of Texas women up to date on cervical cancer screening from 64 percent to 80 percent
  • Timely follow-up, diagnosis and treatment: Ensure 80 percent of women receive diagnostic follow-up and treatment when needed through community outreach, patient navigation, provider training and survivorship support

Overall, the coalition wants to see fewer than four new cases of cervical cancer annually per 100,000 Texas women by 2032, according to a news release from MD Anderson. Currently, Texas has an incidence rate of 9.5 women per 100,000 diagnosed with cervical cancer, compared with 7.5 women per 100,000 nationally.

“Texas has the tools to prevent nearly every case of cervical cancer, but tools can save lives only when people can utilize them,” Dr. Ernest Hawk, vice president and division head of Cancer Prevention and Population Sciences at MD Anderson, said in the release. “The Lone Star Cervical Cancer Elimination Plan gives us a shared roadmap to vaccinate more of our children, screen more of our women and make sure every abnormal result leads to care. With innovations like HPV self-collection and the commitment of partners across the state, elimination is within reach.”

About 40 other hospitals, health care organizations and companies join MD Anderson in the coalition that launched the Lonestar Plan. Those based in Houston include Houston Methodist, Rice University, UTHealth Houston, Texas Children's Hospital, Houston Health Department and others.

The CPRIT also announced its Texans Conquer Cancer Awards and its CPRIT Champion awards during the Innovations Conference this week. Several are based in Houston, including:

  • Zhiqiang An, co-founder of CrossBridge Bio, Director of the Texas Therapeutics Institute, and Vice President of Drug Discovery at the University of Texas Health Science Center at Houston
  • Dr. Abbey Berenson, Director of the UTMB Center for Interdisciplinary Research in Women's Health Care
  • Dr. Michael Taylor, Chair of Pediatric Neuro-Oncology at Texas Children's Cancer and Hematology Center and Director of Texas Children's Pediatric Brain Tumor Research Program

To date, the CPRIT has awarded more than $4.2 billion in grants to fight cancer in the state. Over the summer, it awarded four $2 million grants to institutions in Houston and Bryan for the creation or expansion of “core” cancer research facilities.

Texas Medical Center Innovation recently announced that its $2 million grant would renew its Accelerator for Cancer Therapeutics for five years. Read more from TMCi about the renewal here.

Announcing the 2026 Houston Innovation Awards finalists

Inspirational Innovators

InnovationMap is proud to reveal the finalists for the 2026 Houston Innovation Awards.

The sixth annual Houston Innovation Awards program returns in an all-digital format this fall to honor the best of Houston's innovation ecosystem, including startups, entrepreneurs, mentors, and more.

Finalists were determined by our esteemed panel of judges, comprised of past award winners and InnovationMap editorial leadership.

The panel reviewed applications across 10 prestigious categories to determine our finalists. They will select the winner for each category, except for Startup of the Year, which will be chosen by the public via online voting launching later this month.

We will announce the honoree of our annual Trailblazer Award in the coming weeks, then stay tuned as we unveil all of this year's winners on InnovationMap.com in mid-November.

Get to know our finalists in more detail through editorial spotlights leading up to the winner announcement. Without further ado, here are the 2026 Houston Innovation Awards finalists:

Minority-founded Business

Honoring an innovative startup founded or co-founded by BIPOC or LGBTQ+ representation:

  • AI Made Fun
  • Deep Anchor Solutions
  • HEXAspec
  • Prana Surgical
  • Torres Orbital Mining Inc.

Female-founded Business

Honoring an innovative startup founded or co-founded by a woman:

  • Adair
  • ARIX Technologies
  • Bairitone Health
  • FlowCellutions
  • ParaDocs Health

Energy Transition Business

Honoring an innovative startup providing a solution within renewables, climatetech, clean energy, alternative materials, circular economy and beyond:

  • Capwell Services
  • FlowCellutions
  • Hertha Metals
  • Mars Materials
  • Solidec

Health Tech Business

Honoring an innovative startup within the health and medical technology sectors:

  • Bairitone Health
  • InformAI Inc.
  • Prana Surgical
  • Skybound MedTech

Deep Tech Business

Honoring an innovative startup providing technology solutions based on substantial scientific or engineering challenges, including those in the AI, robotics and space sectors:

  • Casimir
  • Focis AI
  • Machine Saver Inc.
  • Square Robot
  • Venus Aerospace

Startup of the Year (People's Choice)

Honoring a startup celebrating a recent milestone or success. The winner will be selected by the community via an online voting experience:

  • Fluxworks
  • IronLattice
  • Lumino
  • Progress Report
  • Rosarium Health
  • Thread
  • TokenRoster

Scaleup of the Year

Honoring an innovative later-stage startup that's recently reached a significant milestone in company growth:

  • Erock
  • Hertha Metals
  • Venus Aerospace

Incubator/Accelerator of the Year

Honoring a local incubator or accelerator that is championing and fueling the growth of Houston startups:

  • Activate
  • Impact Hub Houston
  • MarMo Innovation

Mentor of the Year

Honoring an individual who dedicates their time and expertise to guide and support budding entrepreneurs:

  • Al Danto, Rice University
  • Eric Rubenstein, New Climate Ventures
  • Jeremy Pitts, Activate
  • Joe Alapat, Liongard
  • Kyle Judah, Rice University's Liu Idea Lab for Innovation & Entrepreneurship
  • Rachel Bickham, Bickham Services Unlimited LLC

Trailblazer Recipient

  • To be announced
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