Annabel Fowler Gatto launched her women's workwear company ahead of the pandemic. Here's how it went. Photo via Pexels

I realized a huge problem professional women were facing, and I launched a company to address it. But then, a pandemic hit.

Eight out of 10 women say they're frustrated and unsupported by traditional workwear brands and their offerings. For many, quality women's workwear means hefty price tags for clothes than, often, have unflattering silhouettes and difficult-to-maintain pieces. It's not a great experience.

Enter Suitably, a professional womenswear brand that offers seasonless staples—all machine washable and under $100. We launched in February 2020 with sky-high momentum. Then, six weeks later, COVID-19 shut down offices worldwide. Overnight, we saw a dip in traffic and the launch momentum slow. But we kept going — reinventing, reimaging, and engineering new ways to serve our customers during a pandemic who were, suddenly, working and interviewing from home. And, now, we're coming out the other side, a stronger, more dynamic and more customer-centric brand than ever. Here's what I learned from launching a workwear brand in a pandemic.

#1 — Be what your customers want and need 

Suitably isn't solely about fashion — it's about helping women be the best versions of themselves, personally and professionally. When COVID-19 struck, that need amplified among our core audience. From our interactions and proactive outreach we heard them loud and clear — they need help, support and guidance now.

We immediately shifted our focus from promoting the collection to doing everything we could to help our community. I made myself available for virtual coffee sessions and hosted over 100 of them during the pandemic. Next, we partnered with a good friend — a psychologist — and churned out free resources on everything from staying positive in a crisis to professional advice, life hacks and everything related to Zoom, from how to dress for a Zoom meeting in every industry to basic Zoom etiquette. The groundswell was immediate and powerful — women craved this information and this connection.

#2 — Be a voice for change

Weeks into the shutdowns when the global workforce was isolated and sweatpants-clad, we launched our next campaign, #GetUpGetDressed. So many women had shared their stories and told us they could barely get out of bed in the morning let alone get dressed and get motivated.

By encouraging women to #GetUpGetDressed — and to share their work-from-home style with Suitably's community — we knew we were doing more than promoting style. We were powering them to shake off the stress and fear, put on something that made them feel good and connect with other women in the Suitably community. Hundreds of women participated and the positive feedback we received was unparallelled. With that, our social footprint grew even more.

#3 — Be careful whose advice you take

Despite the positivity from our community, we still had the naysayers — people eager to share their unsolicited commentary on what we should be doing. The general consensus? Shut down or pivot Suitably ASAP — that a business like ours would likely never be relevant again. We were told to make "Zoom tops." We were told to explore athleisure and masks. We were told to wait for a vaccine then start over — to abandon everything we'd done, the brand equity we worked so hard to build and achieved or pause until the "world is normal".

The reality? None of those people were part of Suitably — and, like us, none of them knew how to navigate a global pandemic. Even so, it would have been easy to fall in line and let a knee-jerk moment of panic destroy everything we'd built. But, instead, we took a breath, took a beat and promised to drown out the noise and the negativity so we could move the business forward, putting the needs of our community first.

#4 — Be confident in yourself

Without the noise we were better able to reassess where we were and what came next — to go back to our roots and to the customer listening we'd been doing for the last few months and use that to set a new course. We knew there was light out there somewhere, and that if we just kept moving towards it, we'd find success.

Admittedly, that was hard sometimes. Even though I knew we had our finger on the pulse of our customers' wants and needs, every day brought a new learning. Despite the chaos, we pushed ahead, following our customers' lead. By the end of June, we had significant data to show that many women in our community, especially those outside of the tri-state area, were returning to the workplace or shopping in anticipation of returning to the workplace. We started to get customer chat's every day asking when new products would be launched, when our restock for sold out pieces was going to occur and we knew it was time to ramp Suitably 100 percent back up.

#5 — Be there for every step of the journey

While the customer journey is rarely linear, the pandemic brought new levels of uncertainty and disconnect. Based on the success of our support and engagement initiatives, we continued to follow our audience on their path — a path that, for many, led right back to the office. We immediately ramped up our messaging, with an eye on helping women get ready to go back — and to feel confident and ready for action the minute they walked through the office doors.

Because of the foundation we'd laid during those first few months — a foundation anchored in trust, understanding and support — our audience leaned in, ready to take that next step into the Suitably experience. Quickly, we were just about back to where we were before COVID-19, not just providing actionable content and a friendly ear but, also, amazing wardrobe pieces that made her feel empowered whether she was back in the office of working from home.

No one knows how to navigate a pandemic — but we all know how to build relationships. That, ultimately, was our strategy. And that, ultimately, is what helped us steer Suitably through the peak of the crisis so we could come out the other side a better, stronger, more dynamic brand than I ever could have imagined with a loyal audience who knows we're truly committed to them and to their success.

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Born and raised in Houston, Annabel Fowler Gatto is the co-founder and CEO of New York-based Suitably.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”