Saigon Hustle owners Sandy Nguyen and Cassie Ghaffar. Courtesy of Saigon Hustle

Anew Houston restaurant will be able to expand courtesy of a $1 million venture capital investment. The Savory Fund selected Houston Vietnamese restaurant Saigon Hustle as the winner of its Million Dollar Restaurant Launch competition.

The private equity firm picked the Houston restaurant from a pool of more than 240 applicants, according to a release. In addition to the money, the investment brings marketing support and access to tools that allow a restaurant to assess its financial performance.

First launched as a ghost kitchen in 2020, Saigon Hustle opened a dedicated brick and mortar restaurant in February. The fast casual concept offers both well-executed takes on classic Vietnamese fare as well as creative interpretations, such as honey-glazed salmon rolls or a twist on the classic bánh xèo: a flour and turmeric crepe filled with braised pork belly, shrimp, and vegetables.

Winning the competition will allow Saigon Hustle founders Cassie Ghaffar and Sandy Nguyen to open a second location of the fast casual restaurant. Nguyen tells CultureMap that the duo have been looking in a number of neighborhoods, including Katy, Memorial, and Bellaire-Meyerland.

"I had tears in my eyes from the overwhelming emotions and we both screamed," Nguyen writes in a message about how she reacted to the news. "This partnership means so much to us."

Asked to elaborate, she notes that Savory Fund's founders have a background in the restaurant industry. They have experience growing restaurants into multi-unit operations.

"More importantly the managing partner also comes from the tech industry," she explains. "They have an amazing team for every aspect to run a successful brand, and that’s what’s so admirable and respectable. We are beyond thrilled at the opportunities we have with them."

Saigon Hustle is one of three establishments Ghaffar and Nguyen operate as part of their Ordinary Concepts hospitality group. They also own Sunday Press, a coffee shop and cafe in Garden Oaks that's adjacent to Saigon Hustle, and Ginger Kale, a healthy eating restaurant in Hermann Park.

“We are thrilled to partner with Cassie and Sandy and select Saigon Hustle as the winner of our Million Dollar Restaurant Launch opportunity,” Savory managing director Andrew K. Smith added. “We are passionate about helping as many restaurateurs as we can because we are restaurant operators at our core. We know the journey from concept to first location and we know the challenges and struggles that accompany growth from first to second unit and we understand them intimately. We hope to create a lifetime worth of success and inspire other concepts to never give up on themselves."

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This article originally ran on CultureMap.

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Houston biotech company tests hard-to-fight cancer therapeutics

fighting cancer

A Houston-based, female-founded biotech company has developed a treatment that could prove to be an effective therapy for a rare blood cancer.

Cellenkos Therapeutics has completed promising Phase 1b testing of its Treg cell therapy, CK0804, in the fight against myelofibrosis. According to a news release from the Cellenkos team, the use of its cord-blood-derived therapeutics could signal a paradigm shift for the treatment of this hard-to-fight cancer.

Cellenkos was founded by MD Anderson Cancer Center physician and professor Simrit Parmar. Her research at the hospital displayed the ability of a unique subset of T cells’ capability to home in on a patient’s bone marrow, restoring immune balance, and potentially halting disease progression.

Myelofibrosis has long been treated primarily with JAK (Janus Kinase) inhibitors, medications that help to block inflammatory enzymes. They work by suppressing the immune response to the blood cancer, but don’t slow the progression of the malady. And they’re not effective for every patient.

“There is a significant need for new therapeutic options for patients living with myelofibrosis who have suboptimal responses to approved JAK inhibitors,” Parmar says. “We are greatly encouraged by the safety profile and early signs of efficacy observed in this patient cohort and look forward to continuing our evaluation of the clinical potential of CK0804 in our planned expansion cohort.”

The expansion cohort is currently enrolling patients with myelofibrosis. What exactly are sufferers dealing with? Myelofibrosis is a chronic disease that causes bone marrow to form scar tissue. This makes it difficult for the body to produce normal blood cells, leaving patients with fatigue, spleen enlargement and night sweats.

Myelofibrosis is rare, with just 16,000 to 18,500 people affected in the United States. But for patients who don’t respond well to JAKs, the prognosis could mean a shorter span than the six-year median survival rate outlined for the disease by Cleveland Clinic.

Helping myelofibrosis patients to thrive isn’t the only goal for Cellenkos right now.

The company seeks to aid people with rare conditions, particularly inflammatory and autoimmune disorders, with the use of CK0804, but also other candidates including one known as CK0801. The latter drug has shown promising efficacy in aplastic anemia, including transfusion independence in treated patients.

The company closed its $15 million series A round led by BVCF Management, based in Shanghai, in 2021. Read more here.

Pioneering Houston biotech startup expands to Brazil for next phase

On the Move

Houston biotech company Cemvita has expanded into Brazil. The company officially established a new subsidiary in the country under the same name.

According to an announcement made earlier this month, the expansion aims to capitalize on Brazil’s progressive regulatory framework, including Brazil’s Fuel of the Future Law, which was enacted in 2024. The company said the expansion also aims to coincide with the 2025 COP30, the UN’s climate change conference, which will be hosted in Brazil in November.

Cemvita utilizes synthetic biology to transform carbon emissions into valuable bio-based chemicals.

“For decades Brazil has pioneered the bioeconomy, and now the time has come to create the future of the circular bioeconomy,” Moji Karimi, CEO of Cemvita, said in a news release. “Our vision is to combine the innovation Cemvita is known for with Brazil’s expertise and resources to create an ecosystem where waste becomes opportunity and sustainability drives growth. By joining forces with Brazilian partners, Cemvita aims to build on Brazil’s storied history in the bioeconomy while laying the groundwork for a circular and sustainable future.”

The Fuel of the Future Law mandates an increase in the biodiesel content of diesel fuel, starting from 15 percent in March and increasing to 20 percent by 2030. It also requires the adoption of Sustainable Aviation Fuel (SAF) and for domestic flights to reduce greenhouse gas emissions by 1 percent starting in 2027, growing to 10 percent reduction by 2037.

Cemvita agreed to a 20-year contract that specified it would supply up to 50 million gallons of SAF annually to United Airlines in 2023.

"This is all made possible by our innovative technology, which transforms carbon waste into value,” Marcio Da Silva, VP of Innovation, said in a news release. “Unlike traditional methods, it requires neither a large land footprint nor clean freshwater, ensuring minimal environmental impact. At the same time, it produces high-value green chemicals—such as sustainable oils and biofuels—without competing with the critical resources needed for food production."

In 2024, Cemvita became capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita quadrupled output at its Houston plant. The company had originally planned to reach this milestone in 2029.

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This story originally appeared on our sister site, EnergyCapitalHTX.