The project was part of a year-long senior design capstone by six students, known as Team Bay-Max, in Rice's Oshman Engineering Design Kitchen. Photo by Jeff Fitlow/Rice University

A team of Rice University engineering students has developed a new way for underwater robots to move around, save power and work more efficiently and quietly.

The robot uses reversible hydrogen fuel cell-based buoyancy control devices that convert water into hydrogen and oxygen (and the reverse) using electricity. Traditional underwater robots use thrusters or large pumps and propellers to change and hold depth, which can be heavy, have higher costs and use more energy. The use of reversible hydrogen fuel cells with balloons, allows the new robot to smoothly adjust its depth with less energy usage, according to a statement from Rice.

The project was part of a year-long senior design capstone by six students, known as Team Bay-Max, in Rice's Oshman Engineering Design Kitchen.

The students—Andrew Bare, Spencer Darwall, Noah Elzner, Rafe Neathery, Ethan Peck and Dan Zislis— won second place in the Willy Revolution Award for Outstanding Innovation at the Huff OEDK Engineering Design Showcase held at the Ion last month.

“Having spent a year on it now and putting so much time into it, getting to see the result of all that work come together is really rewarding,” Peck said in the statement.

“With a project like this, integration was critical,” Zislis added. “Another takeaway for me is the importance of determining a clear scope for any given project. With this robot, we could have focused on a lot of different things. For instance, we could have worked on improving fuel cell efficiency or making a robotic arm. Instead, we chose to keep these other elements simple so as not to divert focus away from the main part, which is the buoyancy control device. This kind of decision-making process is not just part of good engineering, but it’s relevant with everything in life.”

Elzner, for instance, focused on the dashboard that the robot feeds information to as it collects data from different sensors. It displays core system information, real-time graphs of the robot’s location and a simulation of its relative orientation, according to the statement.

Darwall, took a " deep dive into control theory and learn(ed) new software" to incorporate the video game joystick that allows the robot to combine manual control with an automatic stabilizing algorithm.

The proof-of-concept robot has potential applications in environmental monitoring, oceanographic research, and military and industrial tasks, according to Rice.

The team based the project on an academic paper by Houston researchers that showed that fuel cell-enabled depth control could reduce autonomous underwater vehicles’ energy consumption by as much as 85 percent.

It was authored by Rice professor Fathi Ghorbel and members of the University of Houston's Zheng Chen lab.

“This collaborative research aims to develop tetherless continuum soft engines that utilize reversible proton exchange membrane fuel cells and water electrolyzers to drive volume-mass transformation," Ghorbel said in a statement. "Through this design project, the BayMax team proved the efficacy of this technology in AUV interaction with the physical world.”

Ghorbel, Rice mechanical engineering lecturer David Trevas, and Professor in the Practice, Electrical and Computer and Engineering Gary Woods mentored the team.

Last month Rice also held its 24th annual Rice Business Plan Competition, doling out more than $1.5 million in investment and cash prizes to the top teams. Click here to see what student-led startups took home awards.
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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

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Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

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Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.