What's the latest in tech research in Houston? Here are three revolutionary research projects happening right under our noses. Getty Images

Tons of research happens daily at various Houston institutions — from life-saving medical developments to high tech innovations that will affect the greater business community.

In this Houston research roundup, three research projects from three Houston organizations are set to revolutionize their respective industries.

University of Houston researcher explores potential disruption in blockchain

blockchain

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A huge technology question mark within business has been blockchain — how it'll affect the sharing of information and industry as a whole. But, one University of Houston professor and his Texas A&M University colleagues are looking into that potential disruption in a recent paper.

"It's an emerging technology. It's evolving," says Weidong "Larry" Shi, associate professor of computer science at UH, in a UH news release.

Funded by the Borders, Trade, and Immigration Institute, the research has developed into the paper, which was published in the International Journal of Production Research.

A key focus of the research is how blockchain will affect cargo entering the United States, and identifies six pain points within adapting blockchain for cargo management: traceability, dispute resolution, cargo integrity and security, supply chain digitalization, compliance, and trust and stakeholder management, according to the release.

"The wide adoption of blockchain technology in the global SC (supply chain) market is still in its infancy," the article reads. "Industry experts project that on average, it may take about six years for the widespread adoption of blockchain."

Blockchain has the potential to prevent fraud within the global supply chain, among other things.

"The data can't be changed. Everyone (along the supply chain) has a copy. You can add information, but you can't change it," Shi says in the release.

The U.S. Army taps Rice University for network research

Photo by Jeff Fitlow/Rice University

Rice University and the U.S. Army have joined forces for a five-year, $30 million research agreement to modernize the Army — specifically for developing next-generation wireless networks and radio frequency (RF) electronics.

"[The Army Research Laboratory] and Rice will match the right people and capabilities to meet specific challenges, and the cooperative agreement is structured to allow the Army to partner widely across our campus," says Yousif Shamoo, Rice's vice president of research and lead on the ARL partnership, in a recent news release. "One exciting aspect of this partnership is the broader societal benefits. The technologies we're starting with are needed for Army modernization and they could also benefit millions of Americans in communities that still lack high-speed internet."

Without going into too much detail, the two entities are working to advance the Army's existing infrastructure to create networks that can sense attacks and protect themselves by adaption or stealth. The technology has the potential to affect the Army as well as civilians, says Heidi Maupin, the lead ARL contact for the Rice partnership.

"We want to deliver the capability of quickly deploying secure, robust Army communications networks wherever and whenever they're needed," Maupin says in the release. "The technology needed for that will benefit the world by transforming the economics of rural broadband, reducing response times to natural disasters, opening new opportunities for online education and more."

Research out of Baylor College of Medicine advancing information known about vision

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For humans, seeing is pretty simple — just open your eyes. But the process our eyes go through extremely complex, and scientists have had a hard time recreating the process — until now.

Researchers at Baylor College of Medicine in Houston and the University of Tübingen in Germany have developed a novel computational approach that accelerates the brain's ability to identify optimal stimuli. The complete study by the scientists was published in the journal Nature Neuroscience.

"We want to understand how vision works," says senior author Dr. Andreas Tolias, professor and Brown Foundation Endowed Chair of Neuroscience at Baylor. "We approached this study by developing an artificial neural network that predicts the neural activity produced when an animal looks at images. If we can build such an avatar of the visual system, we can perform essentially unlimited experiments on it. Then we can go back and test in real brains with a method we named 'inception loops."

To track neurons and how they work, the researchers tracked brain activity scanning thousands of images.

"Experimenting with these networks revealed some aspects of vision we didn't expect," says Tolias, founder and director of the Center for Neuroscience and Artificial Intelligence at Baylor, in a release. "For instance, we found that the optimal stimulus for some neurons in the early stages of processing in the neocortex were checkerboards, or sharp corners as opposed to simple edges which is what we would have expected according to the current dogma in the field."

The research is ongoing and will only continue to help dissect how the brain sees and interprets visual elements.

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Texas Space Commission doles out $5.8 million to Houston companies

On A Mission

Two Houston-area companies have landed more than $5.8 million in funding from the Texas Space Commission.

The commission granted up to $5.5 million to Houston-based Axiom Space and up to $347,196 to Conroe-based FluxWorks.

The two-year-old commission previously awarded $95.3 million to 14 projects. A little over $34 million remains in the commission-managed Space Exploration and Aeronautics Research Fund.

Axiom Space, a commercial spaceflight company, said the new funding will go toward the development of its orbital data center capabilities. By the end of this year, Axiom plans to launch two free-flying nodes in low-Earth orbit to support its orbital data center operations. More nodes are set to go online in the coming years.

“Axiom Space is actively evaluating how our [orbital data center] architecture can enhance critical U.S. capabilities, including the proposed Golden Dome missile defense architecture,” Jason Aspiotis, global director of in-space data and security at Axiom, said in a news release. “In this context, real-time, around-the-clock availability, secure orbital processing, and AI-driven autonomy are vital for ensuring mission success.”

Founded in 2021, FluxWorks provides magnetic gear technology that was developed at Texas A&M University.

In 2024, FluxWorks was one of two startups to receive the Technology in Space Prize, funded by Boeing and the Center for the Advancement of Science in Space (CASIS), which manages the International Space Station National Laboratory.

FluxWorks is testing the performance of magnetic gear in microgravity environments, such as the International Space Station.

“Gearboxes aim to reduce the mass of motors required in a variety of applications; however, the lubricant needed to make them work properly is not designed for use in extreme environments like space,” according to a 2024 news release about the Technology in Space Prize. “Magnetic gears do not require lubricant, making them an appealing alternative.”

The Texas Space Commission granted $25 million to Houston aerospace companies Starlab Space and Intuitive Machines earlier this year. Read more here.

3 Houston startups named most innovative in Texas by LexisNexis

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Three Houston companies claimed spots on LexisNexis's 10 Most Innovative Startups in Texas report, with two working in the geothermal energy space.

Sage Geosystems claimed the No. 3 spot on the list, and Fervo Energy followed closely behind at No. 5. Fintech unicorn HighRadius rounded out the list of Houston companies at No. 8.

LexisNexis Intellectual Property Solutions compiled the report. It was based on each company's Patent Asset Index, a proprietary metric from LexisNexis that identifies the strength and value of each company’s patent assets based on factors such as patent quality, geographic scope and size of the portfolio.

Houston tied with Austin, each with three companies represented on the list. Caris Life Sciences, a biotechnology company based in Dallas, claimed the top spot with a Patent Asset Index more than 5 times that of its next competitor, Apptronik, an Austin-based AI-powered humanoid robotics company.

“Texas has always been fertile ground for bold entrepreneurs, and these innovative startups carry that tradition forward with strong businesses based on outstanding patent assets,” Marco Richter, senior director of IP analytics and strategy for LexisNexis Intellectual Property Solutions, said in a release. “These companies have proven their innovation by creating the most valuable patent portfolios in a state that’s known for game-changing inventions and cutting-edge technologies.We are pleased to recognize Texas’ most innovative startups for turning their ideas into patented innovations and look forward to watching them scale, disrupt, and thrive on the foundation they’ve laid today.”

This year's list reflects a range in location and industry. Here's the full list of LexisNexis' 10 Most Innovative Startups in Texas, ranked by patent portfolios.

  1. Caris (Dallas)
  2. Apptronik (Austin)
  3. Sage Geosystems (Houston)
  4. HiddenLayer (Austin)
  5. Fervo Energy (Houston)
  6. Plus One Robotics (San Antonio)
  7. Diligent Robotics (Austin)
  8. HighRadius (Houston)
  9. LTK (Dallas)
  10. Eagle Eye Networks (Austin)

Sage Geosystems has partnered on major geothermal projects with the United States Department of Defense's Defense Innovation Unit, the U.S. Air Force and Meta Platforms. Sage's 3-megawatt commercial EarthStore geothermal energy storage facility in Christine, Texas, was expected to be completed by the end of last year.

Fervo Energy fully contracted its flagship 500 MW geothermal development, Cape Station, this spring. Cape Station is currently one of the world’s largest enhanced geothermal systems (EGS) developments, and the station will begin to deliver electricity to the grid in 2026. The company was recently named North American Company of the Year by research and consulting firm Cleantech Group and came in at No. 6 on Time magazine and Statista’s list of America’s Top GreenTech Companies of 2025. It's now considered a unicorn, meaning its valuation as a private company has surpassed $1 billion.

Meanwhile, HighRadius announced earlier this year that it plans to release a fully autonomous finance platform for the "office of the CFO" by 2027. The company reached unicorn status in 2020.

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This article originally appeared on Energy Capital HTX.

UH student earns prestigious award for cancer vaccine research

up-and-comer

Cole Woody, a biology major in the College of Natural Sciences and Mathematics at the University of Houston, has been awarded a Barry Goldwater Scholarship, becoming the first sophomore in UH history to earn the prestigious prize for research in natural sciences, mathematics and engineering.

Woody was recognized for his research on developing potential cancer vaccines through chimeric RNAs. The work specifically investigates how a vaccine can more aggressively target cancers.

Woody developed the MHCole Pipeline, a bioinformatic tool that predicts peptide-HLA binding affinities with nearly 100 percent improvement in data processing efficiency. The MHCole Pipeline aims to find cancer-specific targets and develop personalized vaccines. Woody is also a junior research associate at the UH Sequencing Core and works in Dr. Steven Hsesheng Lin’s lab at MD Anderson Cancer Center.

“Cole’s work ethic and dedication are unmatched,” Preethi Gunaratne, director of the UH Sequencing Core and professor of Biology & Biochemistry at NSM, said in a news release. “He consistently worked 60 to 70 hours a week, committing himself to learning new techniques and coding the MHCole pipeline.”

Woody plans to earn his MD-PhD and has been accepted into the Harvard/MIT MD-PhD Early Access to Research Training (HEART) program. According to UH, recipients of the Goldwater Scholarship often go on to win various nationally prestigious awards.

"Cole’s ability to independently design and implement such a transformative tool at such an early stage in his career demonstrates his exceptional technical acumen and creative problem-solving skills, which should go a long way towards a promising career in immuno-oncology,” Gunaratne added in the release.