Here's how to think about supporting local. Getty images

Businesses everywhere are struggling to survive during these strange times. From the largest global companies to the local mom and pops, these organizations are on the brink of losing the good fight.

Brands we all rely on — including J Crew, JC Penney, Neiman Marcus, Modell's Sporting Goods, and Gold's Gym — have filed or are expected to file for bankruptcy protection in the coming days.

Those are some of the national brands. Local brands come and go with such frequency that many times only the most loyal of consumers are the only ones that realize their demise outside of the owners and employees.

What is a local brand?

Echoing throughout our everyday quarantined lives is the mantra to support your local community businesses. What exactly does that mean? A neighbor of mine is the general manager of a large national retail store in our community. It is not a local business…or is it? I certainly do not want him to fail and lose his job due to a corporate decision to shut down locations. That would affect hundreds of folks in our area that work there.

Then there is the local flower shop that is a one-location mom and pop that a family has poured everything it has into building their retail dream. Now, they face a nightmare of losing it all if things do not turn around soon enough.

What does this all have to do with brand equity?

The equity in your brand is that perceived value customers place in your services or products that makes your brand stand out. It includes brand loyalty, perceived quality and your overall brand awareness. It is why a customer choose one brand over another as price is removed from the equation.

As consumers venture out from the COVID-19 isolation more and more each day, they have decisions to make. Decisions like "Where am I going to spend my money?" This gets even more compounded by the shocking number of furloughed and unemployed people that only weeks ago were humming along fine. Discretionary income is almost becoming a thing of the recent past, meaning every dollar spent beyond rent and food is under extreme scrutiny.

It is at this very point that brand equity can make or break a local business. We all know that the coming months will be trying, and brands are simply trying to hang on to make it through the unprecedented downturn. But guess which brands will come out of this with a chance to realize even more greatness down the road? Those companies that realized from day one the importance of their brand. How people perceive it. How to build value beyond the physical goods or services. The culture of their brand and whether it permeates the organization and every brand touchpoint with consumers.

Think of building brand equity like you would when shopping for home insurance. You do not go get insurance on your home after the fire destroys it. You plan ahead and build home equity by mitigating risk. The same holds for brand equity. You plan ahead and place the importance of an effective brand strategy at the very top of your business priorities.

I have worked on brand strategy from global brands to local and regional brands and you would be surprised to see how brand strategy is undervalued regardless of company size. Too many times (actually, almost always) I see companies large and small treat the brand and marketing strategy as an afterthought, once accounting, purchasing, HR, manufacturing, sales and more are given their proper due.

Brands face pressures daily from all sides including competition, government regulations, changing consumer preferences, technology, advertising expense and more. So those brands that have the focused leadership to build a strong brand platform, as a priority from day one, will win in the long term.

The higher the level of your brand equity in your marketplace, the more likely a consumer will migrate toward your business as they begin thawing their wallets from the pandemic freeze of uncertainty. Spending is under more scrutiny than most of us have ever seen, and brand stewards that have built a strong platform of awareness, value, service, quality and overall experience stand the best chance to earn that sale from loyal customers that appreciate brand equity, even though those customers may not understand how to actually define it.

It's not too late.

While you have the time, even though the slow crawl back to some sort of normalcy can seem overwhelming, prioritize your brand strategy. Spend time each day as you would with accounting and sales to consider how to improve the equity, the value, of your brand among your customer base.

Ask yourself how you can differentiate. What are the ways you can value-add to your services that make your product even more memorable with consumers? What about employee training? Consider whether or not your people believe in your business and have the passion to exemplify those brand attributes you clearly demonstrate day in and day out. Are you following up with customers to build loyalty and learn about how to improve?

Look at the competition, regardless of size, and build a list of what makes your brand better. Then continue to find ways to express that. There is still time if you prioritize differently.

There's an old sugar-packet saying I heard early in my career that I still use today, over 40 years later that goes something like this:

"He Who Has a Thing to Sell
And Goes and Whispers in a Well
Is Not as Apt to Make the Dollars
As He Who Climbs a Tree and Hollers"

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Mike Albrecht is currently a partner and director of business development at Houston-based 9thWonder, a large general market advertising and PR agency based in Houston with offices around the globe.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.